Below are two articles to check out from CreativeBloq.com that talk about the good and the bad of Adobe’s Muse software. The first article is from 2011, which includes a handful of developers’ critique and the other article is a bit more recent (June 2014), talking about Muse CC.
http://www.creativebloq.com/creativity/developers-respond-adobe-muse-8112915
“Web designers are finally understanding the web as a medium in its own right, aspiring to be accessible and device-agnostic. Now Muse strives for print-like perfection, regardless of how many images and conditional comments that requires. This is misguided.” – Tom Muller, Graphic Designer
http://www.creativebloq.com/adobe/muse-cc-hands-review-61411870#null
Also of note is Muse’s good integration with Photoshop CC, which is always important to the design process and moving from mockup through production.
In my opinion, up-and-coming graphic designers are doing themselves a huge disservice by not learning how to code HTML and CSS. They would be holding themselves back from a HUGE area of job opportunity. As a tool that aids in creating a low-touch interactive wireframe mockup, Adobe Muse definitely cuts the time down significantly for designers, and brings it up a notch visually (rather than annotating functionality from a static Photoshop wireframe). However, given alot of the hiccups that Muse presents, getting a high-touch website from the software is far-fetched, and you’ll lose that saved time recoding/redeveloping the site afterwards.
In summary, LEARN CODE KIDS!
-Cory